Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific

We have previously reported induction of transcriptional gene silencing (TGS) of HIV-1 by short hairpin RNA (shRNA) expressed in MOLT-4 cells. The shRNA (termed shPromA) targets the highly conserved tandem NFκB binding sequences of the HIV-1 promoter. Recent articles have reported that TGS mediated...

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Main Authors: Suzuki, Kazuo, Ishida, Takaomi, Yamagishi, Makoto, Ahlenstiel, Chantelle, Swaminathan, Sanjay, Marks, Katharine, Murray, Daniel, McCartney, Erin M, Beard, Michael R, Alexander, Marina, Purcell, Damian FJ, Cooper, David A, Watanabe, Toshiki, Kelleher, Anthony D
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2011
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256422/
https://ncbi.nlm.nih.gov/pubmed/21955498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.6.16264
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