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Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific
We have previously reported induction of transcriptional gene silencing (TGS) of HIV-1 by short hairpin RNA (shRNA) expressed in MOLT-4 cells. The shRNA (termed shPromA) targets the highly conserved tandem NFκB binding sequences of the HIV-1 promoter. Recent articles have reported that TGS mediated...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256422/ https://ncbi.nlm.nih.gov/pubmed/21955498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.6.16264 |
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