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GLT-1 Loss Accelerates Cognitive Deficit Onset in an Alzheimer's Disease Animal Model
Glutamate transporters regulate normal synaptic network interactions and prevent neurotoxicity by rapidly clearing extracellular glutamate. GLT-1, the dominant glutamate transporter in the cerebral cortex and hippocampus, is significantly reduced in Alzheimer's disease (AD). However, the role G...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256092/ https://ncbi.nlm.nih.gov/pubmed/21677376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-110503 |
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