VraSR Two-Component Regulatory System Contributes to mprF-Mediated Decreased Susceptibility to Daptomycin in In Vivo-Selected Clinical Strains of Methicillin-Resistant Staphylococcus aureus

Daptomycin (DAP) is a new class of cyclic lipopeptide antibiotic highly active against methicillin-resistant Staphylococcus aureus (MRSA) infections. Proposed mechanisms involve disruption of the functional integrity of the bacterial membrane in a Ca-dependent manner. In the present work, we investi...

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Asıl Yazarlar: Mehta, Shrenik, Cuirolo, Arabela X., Plata, Konrad B., Riosa, Sarah, Silverman, Jared A., Rubio, Aileen, Rosato, Roberto R., Rosato, Adriana E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256076/
https://ncbi.nlm.nih.gov/pubmed/21986832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00432-10
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