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In Vitro Pharmacodynamics of Vancomycin and Cefazolin Alone and in Combination against Methicillin-Resistant Staphylococcus aureus

Previous studies employing time-kill methods have observed synergistic effects against methicillin-resistant Staphylococcus aureus (MRSA) when a β-lactam is combined with vancomycin. However, these time-kill studies have neglected the importance of human-simulated exposures. We evaluated the effect...

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Main Authors: Hagihara, Mao, Wiskirchen, Dora E., Kuti, Joseph L., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256059/
https://ncbi.nlm.nih.gov/pubmed/22006007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05473-11
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