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In Vitro Pharmacodynamics of Vancomycin against Methicillin-Susceptible and -Resistant Staphylococcus aureus: Considering the Variability in Observed Tissue Exposure

Vancomycin is considered a first-line antibiotic for complicated skin and skin structure infections (cSSSI) because of the risk of methicillin-resistant Staphylococcus aureus (MRSA). The vancomycin exposure of tissue can vary widely in patients with cSSSI, yet most models test only the average expos...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Hamada, Yukihiro, Kuti, Joseph L., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750711/
https://ncbi.nlm.nih.gov/pubmed/26621619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01553-15
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