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In Vitro Pharmacodynamics of Simulated Pulmonary Exposures of Tigecycline Alone and in Combination against Klebsiella pneumoniae Isolates Producing a KPC Carbapenemase

Multidrug-resistant Klebsiella pneumoniae strains that produce a serine carbapenemase (KPC) are emerging worldwide, with few therapeutic options that retain consistent susceptibility. The objective of this study was to determine the effect of combination therapy with tigecycline versus tigecycline a...

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Bibliographische Detailangaben
Hauptverfasser: Wiskirchen, Dora E., Koomanachai, Pornpan, Nicasio, Anthony M., Nicolau, David P., Kuti, Joseph L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067181/
https://ncbi.nlm.nih.gov/pubmed/21282442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01253-10
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