Elevated Cell Wall Chitin in Candida albicans Confers Echinocandin Resistance In Vivo

Candida albicans cells with increased cell wall chitin have reduced echinocandin susceptibility in vitro. The aim of this study was to investigate whether C. albicans cells with elevated chitin levels have reduced echinocandin susceptibility in vivo. BALB/c mice were infected with C. albicans cells...

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Autors principals: Lee, Keunsook K., MacCallum, Donna M., Jacobsen, Mette D., Walker, Louise A., Odds, Frank C., Gow, Neil A. R., Munro, Carol A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256049/
https://ncbi.nlm.nih.gov/pubmed/21986821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00683-11
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