Elevated Cell Wall Chitin in Candida albicans Confers Echinocandin Resistance In Vivo

Candida albicans cells with increased cell wall chitin have reduced echinocandin susceptibility in vitro. The aim of this study was to investigate whether C. albicans cells with elevated chitin levels have reduced echinocandin susceptibility in vivo. BALB/c mice were infected with C. albicans cells...

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Bibliografiske detaljer
Main Authors: Lee, Keunsook K., MacCallum, Donna M., Jacobsen, Mette D., Walker, Louise A., Odds, Frank C., Gow, Neil A. R., Munro, Carol A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256049/
https://ncbi.nlm.nih.gov/pubmed/21986821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00683-11
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