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Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins
Echinocandins are a new generation of novel antifungal agent that inhibit cell wall β(1,3)-glucan synthesis and are normally cidal for the human pathogen Candida albicans. Treatment of C. albicans with low levels of echinocandins stimulated chitin synthase (CHS) gene expression, increased Chs activi...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2271054/ https://ncbi.nlm.nih.gov/pubmed/18389063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000040 |
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