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Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins

Echinocandins are a new generation of novel antifungal agent that inhibit cell wall β(1,3)-glucan synthesis and are normally cidal for the human pathogen Candida albicans. Treatment of C. albicans with low levels of echinocandins stimulated chitin synthase (CHS) gene expression, increased Chs activi...

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Detalhes bibliográficos
Main Authors: Walker, Louise A., Munro, Carol A., de Bruijn, Irene, Lenardon, Megan D., McKinnon, Alastair, Gow, Neil A. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271054/
https://ncbi.nlm.nih.gov/pubmed/18389063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000040
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