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Neddylation and CAND1 Independently Stimulate SCF Ubiquitin Ligase Activity in Candida albicans

SCF (Skp1–cullin/Cdc53–F-box protein) ubiquitin ligases bind substrates via the variable F-box protein and, in conjunction with the RING domain protein Rbx1 and the ubiquitin-conjugating enzyme Ubc3/Cdc34, catalyze substrate ubiquitination. The cullin subunit can be modified covalently by conjugatio...

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Bibliografiske detaljer
Main Authors: Sela, Nadine, Atir-Lande, Avigail, Kornitzer, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255936/
https://ncbi.nlm.nih.gov/pubmed/22080453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05250-11
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