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Mutations at the Base of the Icosahedral Five-Fold Cylinders of Minute Virus of Mice Induce 3′-to-5′ Genome Uncoating and Critically Impair Entry Functions
The linear single-stranded DNA genome of minute virus of mice can be ejected, in a 3′-to-5′ direction, via a cation-linked uncoating reaction that leaves the 5′ end of the DNA firmly complexed with its otherwise intact protein capsid. Here we compare the phenotypes of four mutants, L172T, V40A, N149...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255873/ https://ncbi.nlm.nih.gov/pubmed/22013064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06119-11 |
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