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Single-Chain Fv-Based Anti-HIV Proteins: Potential and Limitations

The existence of very potent, broadly neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1) offers the potential for prophylaxis against HIV-1 infection by passive immunization or gene therapy. Both routes permit the delivery of modified forms of IgGs. Smaller reagents are favo...

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Detalhes bibliográficos
Main Authors: West, Anthony P., Galimidi, Rachel P., Gnanapragasam, Priyanthi N. P., Bjorkman, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255864/
https://ncbi.nlm.nih.gov/pubmed/22013046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05848-11
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