The Virion-Associated Open Reading Frame 49 of Murine Gammaherpesvirus 68 Promotes Viral Replication both In Vitro and In Vivo as a Derepressor of RTA

Replication and transcription activator (RTA), an immediate-early gene, is a key molecular switch to evoke lytic replication of gammaherpesviruses. Open reading frame 49 (ORF49) is conserved among gammaherpesviruses and shown to cooperate with RTA in regulating virus lytic replication. Here we show...

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Detaylı Bibliyografya
Asıl Yazarlar: Noh, Cheol-Woo, Cho, Hye-Jeong, Kang, Hye-Ri, Jin, Hyun Yong, Lee, Shaoying, Deng, Hongyu, Wu, Ting-Ting, Arumugaswami, Vaithilingaraja, Sun, Ren, Song, Moon Jung
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Genome Replication and Regulation of Viral Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255801/
https://ncbi.nlm.nih.gov/pubmed/22090108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05785-11
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