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Recognition of CpG Island Chromatin by KDM2A Requires Direct and Specific Interaction with Linker DNA

Up to 70% of human genes are associated with regions of nonmethylated DNA called CpG islands (S. Saxonov, P. Berg, and D. L. Brutlag, Proc. Natl. Acad. Sci. U. S. A. 103:1412–1417, 2006). Usually associated with the 5′ end of genes, CpG islands are thought to impact gene expression. We previously de...

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Detalhes bibliográficos
Main Authors: Zhou, Jin C., Blackledge, Neil P., Farcas, Anca M., Klose, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255781/
https://ncbi.nlm.nih.gov/pubmed/22083960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06332-11
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