Perinuclear Localization of Internalized Outer Membrane Vesicles Carrying Active Cytolethal Distending Toxin from Aggregatibacter actinomycetemcomitans

Aggregatibacter actinomycetemcomitans is implicated in aggressive forms of periodontitis. Similarly to several other Gram-negative species, this organism produces and excretes a cytolethal distending toxin (CDT), a genotoxin associated with cell distention, G(2) cell cycle arrest, and/or apoptosis i...

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Main Authors: Rompikuntal, Pramod Kumar, Thay, Bernard, Khan, Muhammad Khanzeb, Alanko, Jonna, Penttinen, Anna-Maija, Asikainen, Sirkka, Wai, Sun Nyunt, Oscarsson, Jan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255663/
https://ncbi.nlm.nih.gov/pubmed/22025516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.06069-11
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