Cytolethal Distending Toxin in Isolates of Aggregatibacter actinomycetemcomitans from Ghanaian Adolescents and Association with Serotype and Disease Progression

BACKGROUND AND OBJECTIVES: The cytolethal distending toxin (Cdt) is a highly conserved exotoxin that are produced by a number of Gram negative bacteria, including Aggregatibacter actinomycetemcomitans, and affects mammalian cells by inhibiting cell division and causing apoptosis. A complete cdt-oper...

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Détails bibliographiques
Auteurs principaux: Höglund Åberg, Carola, Antonoglou, Georgios, Haubek, Dorte, Kwamin, Francis, Claesson, Rolf, Johansson, Anders
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683020/
https://ncbi.nlm.nih.gov/pubmed/23922633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065781
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