Short-interfering RNAs Induce Retinal Degeneration via TLR3 and IRF3

The discovery of sequence-specific gene silencing by endogenous double-stranded RNAs (dsRNA) has propelled synthetic short-interfering RNAs (siRNAs) to the forefront of targeted pharmaceutical engineering. The first clinical trials utilized 21-nucleotide (nt) siRNAs for the treatment of neovascular...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Kleinman, Mark E, Kaneko, Hiroki, Cho, Won Gil, Dridi, Sami, Fowler, Benjamin J, Blandford, Alexander D, Albuquerque, Romulo JC, Hirano, Yoshio, Terasaki, Hiroko, Kondo, Mineo, Fujita, Takashi, Ambati, Balamurali K, Tarallo, Valeria, Gelfand, Bradley D, Bogdanovich, Sasha, Baffi, Judit Z, Ambati, Jayakrishna
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255577/
https://ncbi.nlm.nih.gov/pubmed/21988875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.212
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki