Cellular Dysfunction in Diabetes as Maladaptive Response to Mitochondrial Oxidative Stress

Oxidative stress has been implicated in diabetes long-term complications. In this paper, we summarize the growing evidence suggesting that hyperglycemia-induced overproduction of superoxide by mitochondrial electron transport chain triggers a maladaptive response by affecting several metabolic and s...

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Autors principals: Naudi, Alba, Jove, Mariona, Ayala, Victoria, Cassanye, Anna, Serrano, Jose, Gonzalo, Hugo, Boada, Jordi, Prat, Joan, Portero-Otin, Manuel, Pamplona, Reinald
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255456/
https://ncbi.nlm.nih.gov/pubmed/22253615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/696215
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