Antileukemic activity of the HSP70 inhibitor pifithrin-μ in acute leukemia

Heat shock protein (HSP) 70 is aberrantly expressed in different malignancies and has emerged as a promising new target for anticancer therapy. Here, we analyzed the in vitro antileukemic effects of pifithrin-μ (PFT-μ), an inhibitor of inducible HSP70, in acute myeloid leukemia (AML) and acute lymph...

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Autori principali: Kaiser, M, Kühnl, A, Reins, J, Fischer, S, Ortiz-Tanchez, J, Schlee, C, Mochmann, L H, Heesch, S, Benlasfer, O, Hofmann, W-K, Thiel, E, Baldus, C D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255249/
https://ncbi.nlm.nih.gov/pubmed/22829184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.28
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