Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutations

A subgroup of pediatric acute T-lymphoblastic leukemia (T-ALL) was characterized by a gene expression profile comparable to that of early T-cell precursors (ETPs) with a highly unfavorable outcome. We have investigated clinical and molecular characteristics of the ETP-ALL subgroup in adult T-ALL. As...

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Detalhes bibliográficos
Main Authors: Neumann, M, Heesch, S, Gökbuget, N, Schwartz, S, Schlee, C, Benlasfer, O, Farhadi-Sartangi, N, Thibaut, J, Burmeister, T, Hoelzer, D, Hofmann, W-K, Thiel, E, Baldus, C D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270253/
https://ncbi.nlm.nih.gov/pubmed/22829239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.49
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