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Novel Improved Synthesis of HSP70 Inhibitor, Pifithrin-μ. In Vitro Synergy Quantification of Pifithrin-μ Combined with Pt Drugs in Prostate and Colorectal Cancer Cells

We describe a novel improved approach to the synthesis of the important and well-known heat shock protein 70 inhibitor (HSP70), pifithrin-μ, with corresponding and previously unreported characterisation. The first example of a combination study comprising HSP70 inhibitor pifithrin-μ and cisplatin or...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: McKeon, Aoife M., Egan, Alan, Chandanshive, Jay, McMahon, Helena, Griffith, Darren M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273252/
https://ncbi.nlm.nih.gov/pubmed/27455212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21070949
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