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Fabrication, appraisal, and transdermal permeation of sildenafil citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles

Although sildenafil citrate (SC) is used extensively for erectile dysfunction, oral delivery of SC encounters many obstacles. Furthermore, the physicochemical characteristics of this amphoteric drug are challenging for delivery system formulation and transdermal permeation. This article concerns the...

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Autors principals: Elnaggar, Yosra SR, El-Massik, Magda A, Abdallah, Ossama Y
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254264/
https://ncbi.nlm.nih.gov/pubmed/22238508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S25825
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