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Enhanced skin permeation using polyarginine modified nanostructured lipid carriers
The objective of the present study was to investigate the effect of polyarginine chain length on topical delivery of surface modified NLCs. Design of experiments (DOE) was used to optimize number of arginines required to deliver active drug into deeper skin layers. The NLCs were prepared by hot-melt...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412947/ https://ncbi.nlm.nih.gov/pubmed/22617521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.05.011 |
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