Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy

A considerable percentage of rectal cancers are resistant to standard preoperative chemoradiotherapy. Because patients with a priori-resistant tumors do not benefit from multimodal treatment, understanding and overcoming this resistance remains of utmost clinical importance. We recently reported ove...

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Main Authors: Kendziorra, Emil, Ahlborn, Kerstin, Spitzner, Melanie, Rave-Fränk, Margret, Emons, Georg, Gaedcke, Jochen, Kramer, Frank, Wolff, Hendrik A., Becker, Heinz, Beissbarth, Tim, Ebner, Reinhard, Ghadimi, B.Michael, Pukrop, Tobias, Ried, Thomas, Grade, Marian
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Cancer Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254167/
https://ncbi.nlm.nih.gov/pubmed/21983179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr222
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