A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets

Genes that are highly overexpressed in tumor cells can be required for tumor cell survival, and have the potential to be selective therapeutic targets. In an attempt to identify such targets, we combined a functional genomics and a systems biology approach to assess the consequences of RNAi-mediated...

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Detalhes bibliográficos
Main Authors: Grade, Marian, Hummon, Amanda B., Camps, Jordi, Emons, Georg, Spitzner, Melanie, Gaedcke, Jochen, Hoermann, Patrick, Ebner, Reinhard, Becker, Heinz, Difilippantonio, Michael J., Ghadimi, B. Michael, Beissbarth, Tim, Caplen, Natasha J., Ried, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008507/
https://ncbi.nlm.nih.gov/pubmed/20473941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25453
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