טוען...
Antagonistic pleiotropy as a widespread mechanism for the maintenance of polymorphic disease alleles
BACKGROUND: Many serious diseases have a genetic basis which, from an evolutionary point of view, should have been selected against, resulting in very low frequencies. The remarkable sustained prevalence of a number of disease-associated alleles is therefore surprising. We believe that antagonistic...
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| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3254080/ https://ncbi.nlm.nih.gov/pubmed/22151998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-160 |
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