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Nox Enzymes, ROS, and Chronic Disease: An Example of Antagonistic Pleiotropy

Reactive oxygen species (ROS) are considered to be chemically reactive with and damaging to biomolecules including DNA, protein and lipid, and excessive exposure to ROS induces oxidative stress and causes genetic mutations. However, the recently described family of Nox and Duox enzymes generates ROS...

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Bibliografische gegevens
Hoofdauteur: Lambeth, J. David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013737/
https://ncbi.nlm.nih.gov/pubmed/17602948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.03.027
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