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Nox Enzymes, ROS, and Chronic Disease: An Example of Antagonistic Pleiotropy
Reactive oxygen species (ROS) are considered to be chemically reactive with and damaging to biomolecules including DNA, protein and lipid, and excessive exposure to ROS induces oxidative stress and causes genetic mutations. However, the recently described family of Nox and Duox enzymes generates ROS...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2013737/ https://ncbi.nlm.nih.gov/pubmed/17602948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.03.027 |
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