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Leptin Reduces the Expression and Increases the Phosphorylation of the Negative Regulators of GLUT4 Traffic TBC1D1 and TBC1D4 in Muscle of ob/ob Mice

Leptin improves insulin sensitivity in skeletal muscle. Our goal was to determine whether proteins controlling GLUT4 traffic are altered by leptin deficiency and in vivo leptin administration in skeletal muscle of wild type and ob/ob mice. Leptin-deficient ob/ob mice were divided in three groups: co...

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Bibliografske podrobnosti
Main Authors: Sáinz, Neira, Rodríguez, Amaia, Catalán, Victoria, Becerril, Sara, Ramírez, Beatriz, Lancha, Andoni, Burgos-Ramos, Emma, Gómez-Ambrosi, Javier, Frühbeck, Gema
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253781/
https://ncbi.nlm.nih.gov/pubmed/22253718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029389
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