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Leptin Administration Favors Muscle Mass Accretion by Decreasing FoxO3a and Increasing PGC-1α in ob/ob Mice

Absence of leptin has been associated with reduced skeletal muscle mass in leptin-deficient ob/ob mice. The aim of our study was to examine the effect of leptin on the catabolic and anabolic pathways regulating muscle mass. Gastrocnemius, extensor digitorum longus and soleus muscle mass as well as f...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sáinz, Neira, Rodríguez, Amaia, Catalán, Victoria, Becerril, Sara, Ramírez, Beatriz, Gómez-Ambrosi, Javier, Frühbeck, Gema
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733298/
https://ncbi.nlm.nih.gov/pubmed/19730740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006808
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