Leptin Reduces the Expression and Increases the Phosphorylation of the Negative Regulators of GLUT4 Traffic TBC1D1 and TBC1D4 in Muscle of ob/ob Mice

Leptin improves insulin sensitivity in skeletal muscle. Our goal was to determine whether proteins controlling GLUT4 traffic are altered by leptin deficiency and in vivo leptin administration in skeletal muscle of wild type and ob/ob mice. Leptin-deficient ob/ob mice were divided in three groups: co...

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Detalhes bibliográficos
Main Authors: Sáinz, Neira, Rodríguez, Amaia, Catalán, Victoria, Becerril, Sara, Ramírez, Beatriz, Lancha, Andoni, Burgos-Ramos, Emma, Gómez-Ambrosi, Javier, Frühbeck, Gema
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253781/
https://ncbi.nlm.nih.gov/pubmed/22253718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029389
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