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A Note on False Positives and Power in G × E Modelling of Twin Data

The variance components models for gene–environment interaction proposed by Purcell in 2002 are widely used. In both the bivariate and the univariate parameterization of these models, the variance decomposition of trait T is a function of moderator M. We show that if M and T are correlated, and mode...

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Autori principali: van der Sluis, Sophie, Posthuma, Danielle, Dolan, Conor V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253285/
https://ncbi.nlm.nih.gov/pubmed/21748401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10519-011-9480-3
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