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A Note on False Positives and Power in G × E Modelling of Twin Data

The variance components models for gene–environment interaction proposed by Purcell in 2002 are widely used. In both the bivariate and the univariate parameterization of these models, the variance decomposition of trait T is a function of moderator M. We show that if M and T are correlated, and mode...

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Detalhes bibliográficos
Main Authors: van der Sluis, Sophie, Posthuma, Danielle, Dolan, Conor V.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253285/
https://ncbi.nlm.nih.gov/pubmed/21748401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10519-011-9480-3
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