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A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands
A limited set of T cell receptor (TCR) variable (V) gene segments are used to create a repertoire of TCRs that recognize all major histocompatibility complex (MHC) ligands within a species. How individual αβTCRs are constructed to specifically recognize a limited set of MHC ligands is unclear. Here...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253227/ https://ncbi.nlm.nih.gov/pubmed/22101158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.10.012 |
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