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Dickkopf1: A tumor suppressor or metastasis promoter?

Dickkopf1 (DKK1), a secreted inhibitor of the Wnt/β-catenin pathway, is a negative regulator of bone formation. DKK1 acts as a switch that transitions prostate cancer bone metastases from osteolytic to osteoblastic and also is an active indicator of poor outcome for multiple myeloma. However, in oth...

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Detalhes bibliográficos
Main Authors: Menezes, Mitchell E., Devine, Daniel J., Shevde, Lalita A., Samant, Rajeev S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253198/
https://ncbi.nlm.nih.gov/pubmed/21953410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26449
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