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Dickkopf1: A tumor suppressor or metastasis promoter?
Dickkopf1 (DKK1), a secreted inhibitor of the Wnt/β-catenin pathway, is a negative regulator of bone formation. DKK1 acts as a switch that transitions prostate cancer bone metastases from osteolytic to osteoblastic and also is an active indicator of poor outcome for multiple myeloma. However, in oth...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253198/ https://ncbi.nlm.nih.gov/pubmed/21953410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26449 |
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