Trihydrophobin 1 Phosphorylation by c-Src Regulates MAPK/ERK Signaling and Cell Migration

c-Src activates Ras-MAPK/ERK signaling pathway and regulates cell migration, while trihydrophobin 1 (TH1) inhibits MAPK/ERK activation and cell migration through interaction with A-Raf and PAK1 and inhibiting their kinase activities. Here we show that c-Src interacts with TH1 by GST-pull down assay,...

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Autori principali: Wu, Weibin, Sun, Zhichao, Wu, Jingwen, Peng, Xiaomin, Gan, Huacheng, Zhang, Chunyi, Ji, Lingling, Xie, Jianhui, Zhu, Haiyan, Ren, Shifang, Gu, Jianxin, Zhang, Songwen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253115/
https://ncbi.nlm.nih.gov/pubmed/22238675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029920
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