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Synthesis of (−)-julocrotine and a diversity oriented Ugi-approach to analogues and probes
An improved total synthesis of (−)-julocrotine in three steps from Cbz-glutamine, in 51% overall yield, is presented. To demonstrate the potential of the heterocyclic moiety for diversity oriented synthesis, a series of (−)-julocrotine analogues was synthesized by employing the heterocyclic precurso...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252850/ https://ncbi.nlm.nih.gov/pubmed/22238524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.175 |
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