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Diversity-oriented synthesis of analogues of the novel macrocyclic peptide FR-225497 through late stage functionalization
A concise synthetic approach to a class of biologically interesting cyclic tetrapeptides is reported which involves a late-stage functionalization of a macrocyclic scaffold through cross metathesis in an attempt to create diversity. The utility of this protocol is demonstrated through the preparatio...
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| Publicado no: | Beilstein J Org Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685926/ https://ncbi.nlm.nih.gov/pubmed/26734096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.270 |
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