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Diversity-oriented synthesis of analogues of the novel macrocyclic peptide FR-225497 through late stage functionalization

A concise synthetic approach to a class of biologically interesting cyclic tetrapeptides is reported which involves a late-stage functionalization of a macrocyclic scaffold through cross metathesis in an attempt to create diversity. The utility of this protocol is demonstrated through the preparatio...

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Bibliografski detalji
Izdano u:Beilstein J Org Chem
Glavni autori: Mukherjee, Jyotiprasad, Sil, Suman, Chattopadhyay, Shital Kumar
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685926/
https://ncbi.nlm.nih.gov/pubmed/26734096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.270
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