Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells

Numerous chromatin regulators are required for embryonic stem (ES) cell self-renewal and pluripotency, but few have been studied in detail. Here, we examine the roles of several chromatin regulators whose loss affects the pluripotent state of ES cells. We find that Mbd3 and Brg1 antagonistically reg...

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Main Authors: Yildirim, Ozlem, Li, Ruowang, Hung, Jui-Hung, Chen, Poshen B., Dong, Xianjun, Ee, Ly-sha, Weng, Zhiping, Rando, Oliver J., Fazzio, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252821/
https://ncbi.nlm.nih.gov/pubmed/22196727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.11.054
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