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DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells

Cytosine methylation is an epigenetic and regulatory mark that functions in part through recruitment of chromatin remodeling complexes containing methyl-CpG binding domain (MBD) proteins. Two MBD proteins, Mbd2 and Mbd3, were previously shown to bind methylated or hydroxymethylated DNA, respectively...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hainer, Sarah J, McCannell, Kurtis N, Yu, Jun, Ee, Ly-Sha, Zhu, Lihua J, Rando, Oliver J, Fazzio, Thomas G
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111885/
https://ncbi.nlm.nih.gov/pubmed/27849519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21964
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