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Suppression of Farnesyltransferase Activity in Acute Myeloid Leukemia and Myelodysplastic Syndrome: Current Understanding and Recommended Use of Tipifarnib

IMPORTANCE OF THE FIELD: Acute Myeloid Leukemia (AML) and myelodysplastic syndrome (MDS) incidence in the United States increase with age. Given the progressive aging of the general population, incidence of these diseses is likely to continue to rise in the future. There is an earnest need for thera...

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Autori principali: Epling-Burnette, P.K., Loughran, Thomas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252817/
https://ncbi.nlm.nih.gov/pubmed/20402600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543781003801076
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