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Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis
Early during Gram-negative sepsis, excessive release of pro-inflammatory cytokines can cause septic shock that is often followed by a state of immune paralysis characterized by the failure to mount adaptive immunity towards secondary microbial infections. Especially, the early mechanisms responsible...
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Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Nature Publishing Group
2012
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252580/ https://ncbi.nlm.nih.gov/pubmed/22036947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.380 |
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