Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis

Early during Gram-negative sepsis, excessive release of pro-inflammatory cytokines can cause septic shock that is often followed by a state of immune paralysis characterized by the failure to mount adaptive immunity towards secondary microbial infections. Especially, the early mechanisms responsible...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Schwandt, Timo, Schumak, Beatrix, Gielen, Gerrit H, Jüngerkes, Frank, Schmidbauer, Patricia, Klocke, Katrin, Staratschek-Jox, Andrea, van Rooijen, Niko, Kraal, Georg, Ludwig-Portugall, Isis, Franken, Lars, Wehner, Sven, Kalff, Jörg C, Weber, Olaf, Kirschning, Carsten, Coch, Christoph, Kalinke, Ulrich, Wenzel, Jörg, Kurts, Christian, Zawatzky, Rainer, Holzmann, Bernhard, Layland, Laura, Schultze, Joachim L, Burgdorf, Sven, den Haan, Joke MM, Knolle, Percy A, Limmer, Andreas
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group 2012
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252580/
https://ncbi.nlm.nih.gov/pubmed/22036947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.380
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