Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis

Early during Gram-negative sepsis, excessive release of pro-inflammatory cytokines can cause septic shock that is often followed by a state of immune paralysis characterized by the failure to mount adaptive immunity towards secondary microbial infections. Especially, the early mechanisms responsible...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schwandt, Timo, Schumak, Beatrix, Gielen, Gerrit H, Jüngerkes, Frank, Schmidbauer, Patricia, Klocke, Katrin, Staratschek-Jox, Andrea, van Rooijen, Niko, Kraal, Georg, Ludwig-Portugall, Isis, Franken, Lars, Wehner, Sven, Kalff, Jörg C, Weber, Olaf, Kirschning, Carsten, Coch, Christoph, Kalinke, Ulrich, Wenzel, Jörg, Kurts, Christian, Zawatzky, Rainer, Holzmann, Bernhard, Layland, Laura, Schultze, Joachim L, Burgdorf, Sven, den Haan, Joke MM, Knolle, Percy A, Limmer, Andreas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252580/
https://ncbi.nlm.nih.gov/pubmed/22036947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.380
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