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MHC Class I negatively regulates synapse density during the establishment of cortical connections
Major histocompatibility complex class I (MHCI) molecules modulate activity-dependent refinement and plasticity. Here, we show that MHCI also negatively regulates the density and function of cortical synapses during their initial establishment both in vitro and in vivo. MHCI molecules are expressed...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251641/ https://ncbi.nlm.nih.gov/pubmed/21358642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2764 |
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