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MHCI Requires MEF2 Transcription Factors to Negatively Regulate Synapse Density during Development and in Disease

Major histocompatibility complex class I (MHCI) molecules negatively regulate cortical connections and are implicated in neurodevelopmental disorders, including autism spectrum disorders and schizophrenia. However, the mechanisms that mediate these effects are unknown. Here, we report a novel MHCI s...

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Autors principals: Elmer, Bradford M., Estes, Myka L., Barrow, Stephanie L., McAllister, A. Kimberley
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755720/
https://ncbi.nlm.nih.gov/pubmed/23966700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2366-13.2013
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