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Critical role for perforin and Fas-dependent killing of dendritic cells in the control of inflammation
After stimulation of antigen-specific T cells, dendritic cell (DCs) are susceptible to killing by these activated T cells that involve perforin and Fas-dependent mechanisms. Fas-dependent DC apoptosis has been shown to limit DC accumulation and prevent the development of autoimmunity. However, a rol...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251225/ https://ncbi.nlm.nih.gov/pubmed/22042696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-363994 |
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