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Critical role for perforin and Fas-dependent killing of dendritic cells in the control of inflammation

After stimulation of antigen-specific T cells, dendritic cell (DCs) are susceptible to killing by these activated T cells that involve perforin and Fas-dependent mechanisms. Fas-dependent DC apoptosis has been shown to limit DC accumulation and prevent the development of autoimmunity. However, a rol...

詳細記述

保存先:
書誌詳細
主要な著者: Chen, Min, Felix, Kumar, Wang, Jin
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251225/
https://ncbi.nlm.nih.gov/pubmed/22042696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-363994
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