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Histamine 3 Receptor Activation Reduces the Expression of Neuronal Angiotensin II Type 1 Receptors in the Heart
In severe myocardial ischemia, histamine 3 (H(3)) receptor activation affords cardioprotection by preventing excessive norepinephrine release and arrhythmias; pivotal to this action is the inhibition of neuronal Na(+)/H(+) exchanger (NHE). Conversely, angiotensin II, formed locally by mast cell-deri...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251025/ https://ncbi.nlm.nih.gov/pubmed/22011436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.187765 |
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