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Histamine 3 Receptor Activation Reduces the Expression of Neuronal Angiotensin II Type 1 Receptors in the Heart

In severe myocardial ischemia, histamine 3 (H(3)) receptor activation affords cardioprotection by preventing excessive norepinephrine release and arrhythmias; pivotal to this action is the inhibition of neuronal Na(+)/H(+) exchanger (NHE). Conversely, angiotensin II, formed locally by mast cell-deri...

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Detalhes bibliográficos
Main Authors: Hashikawa-Hobara, Narumi, Chan, Noel Yan-Ki, Levi, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251025/
https://ncbi.nlm.nih.gov/pubmed/22011436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.187765
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